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Martha Carlin's avatar

I could go on and on about this one. But I won’t here - I’ve looked the microbiome of smokers and people who quit smoking from our poop sample database. And it jumped off the page at me. Key functional genes are opposit of the PD samples I’ve been looking at for years. 😉 but people who quit look like PD microbiome. And it turns out a fair amount of our PD cohort were former smokers.

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Stephen Skolnick's avatar

Ohhh I knew you'd have hot takes on this one! I'll shoot you an email and we can get down into the KEGG weeds

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Raja's avatar

Did the former smokers with PD have constipation?

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Martha Carlin's avatar

I would have to dig back in to the meta data to look for that. Off the top of my head I don't remember.

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Maxwell's avatar

Related: tobacco smoking appears to have an ameliorative effect on ulcerative colitis in some cases (though the few meta-reviews I’ve seen definitely make me want to put more of an emphasis on *some*)

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